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VOL. 7, ISSUE 3 (2025)
Endocrine toxicity induced by plant growth regulators
Authors
Alfin Mariya, Adheena Xavier, Krishnanjana VJ, Nisha AR4, Sujith S
Abstract
Plant growth regulators (PGRs), are widely
used to enhance agricultural productivity and have emerged as potential
endocrine-disrupting chemicals (EDCs) with significant implications for animal
and human health. Though they modulate plant growth through hormone like
activity in numerous ways. This review explores the mechanisms and pathways
through which PGRs induce toxicity in endocrine organs. PGRs can impair hormone
biosynthesis, receptor signalling and metabolic enzyme function. It would lead
to reproductive toxicity, developmental anomalies, neurological effects and
systemic organ damage. Molecular and histopathological findings demonstrate PGR
induced apoptosis, oxidative stress, DNA damage, and alterations in
steroidogenesis and gene expression. These disruptions underline the need for
toxicological evaluations and safer agricultural practices to minimize
environmental and health risks associated with PGR exposure.
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Pages:33-37
How to cite this article:
Alfin Mariya, Adheena Xavier, Krishnanjana VJ, Nisha AR4, Sujith S "Endocrine toxicity induced by plant growth regulators". International Journal of Agriculture and Plant Science, Vol 7, Issue 3, 2025, Pages 33-37
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