Two consecutive seasons of 2011- 2012 and 2012- 2013 were studied at Elsuki area, Sinnar State, Sudan to assess the seasonal changes of the vegetation cover, using five major transects each one 3000m length and 10m width, of total area 150.000m². 75 quadrates and 5 pellets transect were used to assess changes in the flora of the area. The results showed that there were sixty-four species decreased by 70.3% while they increased by 26.6% and normal percentage of 3.13%. Main decrease species was Commelina amplexicaul is (30.08%), where main increase was Srtiga hermothica (0.75%). Fifteen tree species were recorded, decreased by 53.3% while they increased by 40% and normal percentage of 6.7%. Main decrease species was Acacia seyal var seyal (8.83%), where main increase species was Acacia senegal (17.39%). Nine shrub species were recorded decreased by 66.7% while they increased by 22.2% and normal percentage of 11.1%. Main decreases species was Acacia oerfota (36.65%), where main increase was Stereospermum kunthianum (0.31). Increasing or decreasing in vegetation cover maybe attributed to seasonal climate changes, human activities or grazing process, so it’s to be recommended more investigations to record these changes to conserve Elsuki vegetation cover.